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The McKenzie System With Arthritic Knees: Do Some Knees Respond to Specific Exercise More Than General or no Exercise

L

Lawson Health Research Institute

Status and phase

Completed
Phase 2
Phase 1

Conditions

Knee Osteoarthritis

Treatments

Procedure: Exercise
Procedure: Evidence based exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT01641874
IMDTRF (Other Grant/Funding Number)
16399E

Details and patient eligibility

About

The purpose of the study is to explore if a subgroup of people with osteoarthritic knees can be identified using the McKenzie System of Mechanical Diagnosis and Therapy.

In the spine this subgroup, termed derangement,has been shown to respond rapidly to specific directional exercises.

The trial will explore whether these derangements in the knee respond to specific exercises compared to a control group with no exercises and non-derangement knees given general exercises.

Full description

The Mechanical Diagnosis and Therapy (MDT) approach has been extensively used to classify and treat patients with spinal pain. Studies have shown this approach to be valid, reliable and able to predict outcome. Although the approach has been used for extremity joints there is no research on using this approach to classify individuals presenting with knee osteoarthritis.

An assessment tool that could potentially identify a subgroup of patients who would experience dramatic and rapid improvement to conservative care would be valuable.

Patients with an "osteoarthritic knee" diagnosis will be recruited after a consultation with an orthopaedic surgeon. Patients who consent to participate will be randomized into an intervention group and a control group. Baseline self reported function and pain will be collected. The control group will continue as planned on the waiting list for either a follow up orthopaedic consultation or for knee surgery. The intervention group will be assessed by one of three McKenzie credentialed therapist over 3 assessment sessions. The therapist will classify the patients as either having a "derangement" or not. Those classified as a derangement will have 2-3 follow up sessions and will be given direction specific exercises consistent with the principles of the McKenzie System over 2 weeks. Those patients who were not classified as derangements will be given 2-3 sessions of evidenced based osteoarthritis treatment consisting of strengthening exercises and advice on aerobic fitness exercise. At 2 weeks both groups will have baseline measures reassessed and will be discharged. Follow-up by telephone at 3 months and 1 year will reassess functional and pain measures.

Due to the high prevalence of knee osteoarthritis and the associated economic burden on our health care system it is important to investigate if physiotherapists are able to predict who will respond to conservative therapy. Classifying individuals with knee osteoarthritis into rapid responders or non responders to short-term physiotherapy treatment will allow more expensive medical evaluation and intervention to be directed to appropriate patients and avoid unnecessary treatment for patients likely to recover from less costly therapy.

Enrollment

180 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Diagnosed with knee osteoarthritis
  • Pain for longer than four months
  • Knee X-ray/CT/MRI showing osteoarthritic changes
  • Able to attend physiotherapy 2-3 times per week for 2 weeks
  • Able to participate in exercise based therapy

Exclusion criteria

  • Unable to provide informed consent
  • Unable to understand written or spoken English
  • Neurological conditions

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

180 participants in 3 patient groups

Specific directional exercise
Experimental group
Description:
During the assessment a specific exercise will be identified for this group. The exercise will consist of a repeated specific end range movement of the knee
Treatment:
Procedure: Exercise
Evidence based exercise
Active Comparator group
Description:
Quadriceps strengthening and advice on aerobic exercises will be given
Treatment:
Procedure: Evidence based exercise
No intervention
No Intervention group
Description:
Patient waits on the surgeons waiting list for next appointment or for planned knee surgery

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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