The Mechanism and Prognosis of Pulmonary Circulation Dysfunction

Chinese Academy of Medical Sciences, Fuwai Hospital

Status: Unknown

Conditions: VTE

Study type: Observational

Funder types: Other

Identifiers

NCT03616366

2017-I2M-1-009

Details and patient eligibility

About

Venous thromboembolism (VTE) is a condition which influenced by both environmental and genetic factors. This study is going to explore new significant Single nucleotide polymorphisms (SNPs) associated with VTE by Genome-Wide Association Studies (GWAS) and bioinformatics analysis. Transcriptomics and cytokine antibody array are also used to find new biomarkers of VTE's early diagnosis, severity and prognosis.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 14+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Chinese Han population older than 14 years old
• Acute VTE patients diagnosed in 1 month
• With informed consent

Exclusion criteria

• Patients with psychosis
• Patients with contraindications for computed tomographic pulmonary angiography (CTPA)
• Chronic VTE
• Recurrence of chronic VTE