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The Mechanism of Melanocyte Self-Assembly on Biomaterials and the Functional Analysis

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National Taiwan University

Status

Unknown

Conditions

Vitiligo
Melanocyte

Treatments

Behavioral: melanocyte self-assembly and functional analysis

Study type

Observational

Funder types

Other

Identifiers

NCT00509314
9561703036

Details and patient eligibility

About

The aim of this study is to survey melanocytes in the ability of self-assembly on biomaterials and functional analysis in vitro. Also, this study may provide a better way for treatment of vitiligo after understanding the functional aspects of melanocytes.

Full description

Vitiligo is a chronic disease that causes loss of melanocyte and pigment of the skin. Traditional treatments for vitiligo including topical corticosteroids and phototherapy lead to limited clinical effects. Autologous melanocyte transplantation is another way to treat vitiligo. However, the effect is largely affected by whether cultivated melanocytes are successfully uptaken by vitiliginous skin. The aim of this study is to survey the self-assembly on biomaterials and functional analysis. In the long run, this study may provide a better way for treatment of vitiligo.

Enrollment

400 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients receiving cosmetic removal of moles

Exclusion criteria

  • No special exclusion criteria

Trial contacts and locations

1

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Central trial contact

Sung-Jan Lin, MD PhD

Data sourced from clinicaltrials.gov

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