The Medical Management in Patients Exposed to Weapons of Mass Destruction (CBRNEObs)

St. Justine's Hospital

Status: Invitation-only

Conditions: Acute Respiratory Distress Syndrome; Chemicals; Intoxication; Medical Emergencies; Distress Respiratory Syndrome; Chemical Injury

Treatments: Procedure: Clinical interventions performed in acute settings (contaminated environment); Procedure: Protection (clinician and patient); Procedure: Decontamination (clinician and patient)

Study type: Observational

Funder types: Other

Identifiers

NCT05026645

2020-2561

Details and patient eligibility

About

Observation study measuring medical response in contaminated environment.

Full description

This is an ongoing multicentric observational study that aims to assess the medical response to chemical, biological, radiological, nuclear, explosive (cbrne) events during the last five (5) decades (i.e.: 1970-2020), and in any future cbrne attack that might occur within the next 15 years (i.e.: 2021-2036). Of note, the data collection will be performed retrospectively and after sites review ethic board (REB) approval.

Enrollment: 1,000 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

i. a CBRNE attack caused at least one casualty who required the assistance of the participating health care system (e.g.: physicians, nurses, paramedics and other health-care specialists of a medical facility) during a medical extraction from the incident site until admission to a medical facility;

ii. Patients are eligible if they were exposed to the CBRNE attack;

iii. Medical information concerning the CBRNE exposures, even if partial, is accessible to health care professionals for the purposes of filling out the online case report form (eCRF);

iv. Participants must be able to complete the online case report form in English; and

v. The approval of an Ethics Review Board is obtained by each medical centre participant.

Exclusion criteria

A negative response to any of the inclusion criteria results in an exclusion.

Trial design

1,000 participants in 8 patient groups

adult inflicted by a CBRNE weapon

Description:

Part of the Population is being studied includes any individual who was affected by CBRNE attacks and needed an intervention of the healthcare system.

Treatment:

Procedure: Decontamination (clinician and patient)

Procedure: Protection (clinician and patient)

Procedure: Clinical interventions performed in acute settings (contaminated environment)

Infant inflicted by a CBRNE weapon

Description:

Part of the population is being studied includes any individual who was affected by CBRNE attacks and needed an intervention of the healthcare system.

Treatment:

Procedure: Decontamination (clinician and patient)

Procedure: Protection (clinician and patient)

Procedure: Clinical interventions performed in acute settings (contaminated environment)

Women inflicted by a CBRNE weapon

Description:

Part of the Population is being studied includes any individual who was affected by CBRNE attacks and needed an intervention of the healthcare system.

Treatment:

Procedure: Decontamination (clinician and patient)

Procedure: Protection (clinician and patient)

Procedure: Clinical interventions performed in acute settings (contaminated environment)

Men inflicted by a CBRNE weapon

Description:

Part of the Population is being studied includes any individual who was affected by CBRNE attacks and needed an intervention of the healthcare system.

Treatment:

Procedure: Decontamination (clinician and patient)

Procedure: Protection (clinician and patient)

Procedure: Clinical interventions performed in acute settings (contaminated environment)

Elderly inflicted by a CBRNE weapon

Description:

Part of the Population is being studied includes any individual who was affected by CBRNE attacks and needed an intervention of the healthcare system.

Treatment:

Procedure: Decontamination (clinician and patient)

Procedure: Protection (clinician and patient)

Procedure: Clinical interventions performed in acute settings (contaminated environment)

Diagnosed with chronic disease(s) inflicted by a CBRNE weapon

Description:

Part of the Population is being studied includes any individual who was affected by CBRNE attacks and needed an intervention of the healthcare system.

Treatment:

Procedure: Decontamination (clinician and patient)

Procedure: Protection (clinician and patient)

Procedure: Clinical interventions performed in acute settings (contaminated environment)

Clinician (adult) whom performs his/her clinical interventions

Description:

Clinician (adult) whom performs his/her clinical interventions while integrating competences in protections and decontamination. Part of the Population is being studied includes any individual who was affected by CBRNE attacks and needed an intervention of the healthcare system. This is the case of when the clinician is required to ensure safety toward his/her patient while performing his/her interventions \& procedures.

Treatment:

Procedure: Decontamination (clinician and patient)

Procedure: Protection (clinician and patient)

Procedure: Clinical interventions performed in acute settings (contaminated environment)

Clinician (adult) injured by duties circumstances

Description:

Part of the Population is being studied includes any individual who was affected by CBRNE attacks and needed an intervention of the healthcare system. This is the case of when the clinician becomes inflicted by a CBRNE weapon while intervening toward contaminated patient due to any failure in protection and decontamination.

Treatment:

Procedure: Decontamination (clinician and patient)

Procedure: Protection (clinician and patient)

Procedure: Clinical interventions performed in acute settings (contaminated environment)