The Metabolic and Circadian Effects of Shift Work (OPTI-SHIFT)

Tinh-Hai Collet, MD

Status

Completed

Conditions

Shift Work Schedule

Treatments

Other: Exposure to shift work

Study type

Observational

Funder types

Other

Identifiers

NCT05177965

2021-01088

Details and patient eligibility

About

In an exploratory observational pilot study, the investigators will focus on the effects of short-term circadian misalignment induced by shift work on multidimensional measurements including glucose excursion, metabolic health, circadian rhythms (measured in vitro and in vivo), sleep/wake cycles and ambient light, eating and activity patterns, well-being and attention.

Enrollment

72 patients

Sex

All

Ages

20 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Men and women
Age 20-50 years
Working ≥ 80% full-time equivalent over the previous month and during the study
Working night shifts (i.e. shifts that comprise working hours between 23h and 06h) in rotation with day shifts (i.e. shifts that comprise working hours between 06h and 20h)
Planned to work at least 3 consecutive night shifts during the study preceded by at least a day off or day shift
Planned to work at least 3 consecutive day shifts during the study
Confident use of a smartphone compatible with the study application (iOS, Android) and able to regularly take pictures of consumed food/drinks
Able to give a fully informed consent and follow the study procedures

Exclusion criteria

Planned or current pregnancy during the study
Menopausal women
Major illness or hospitalization over the previous month
Carries a pacemaker, pump or other medical device that can be disabled by a magnet
Major mental illness
Trip to a different time zone (≥ 2-hour time difference) over the previous month or planned during the study
Enrolled in an interventional clinical trial (potentially interfering with the main outcomes) over the previous month or planned during the study