The Metabolomics of Intestinal Polyps of Different Pathological Types and TCM Syndromes and TCM Constitution Types

Harbin Medical University

Status: Completed

Conditions: Intestinal Polyps

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT02986308

Wei Xu

Details and patient eligibility

About

The aim of this study is to confirm the TCM syndrome types and TCM constitution classifications of the patients with intestinal polyps via on-site epidemiological survey, to analyze metabolomics of the serum samples of intestinal polyps and healthy volunteers, and to study the metabolomics differences of the two populations and the metabolomics variations of the patients with intestinal polyps of pre-polypectomy and post-polypectomy. Finally, this study is to investigate the serum metabolomics variations of patients with intestinal polyps of pre-polypectomy and post-polypectomy and the relationship with their TCM syndrome types and TCM constitution classifications, to determine the correlation among pathology, TCM constitution, TCM syndrome types and the metabonomics variations of patients with intestinal polyps.

Enrollment: 1,659 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Age 20 to 80,all genders;
2. Intestinal polyps were found by colonoscopy;
3. The patients are scheduled for polypectomy;
4. Preoperative examinations were completed;
5. Performance status 0-1;
6. Diet has well controlled prior to the operation;
7. Patients or their statutory agent have signed the informed consent forms.

Exclusion criteria

1. The patient has not diagnosed by colonoscopy;
2. The patient has surgical contraindication;
3. Patients in pregnant or lactational period ;
4. Psychopath;
5. The patient is in drug trial.

Trial design

1,659 participants in 2 patient groups

Intestinal Polyps

Description:

The patients who were diagnosed with Intestinal Polyps.

Treatment:

Other: No intervention

Normal colonoscopy

Description:

People who were diagnosed by colonoscopy without intestinal polyps.

Treatment:

Other: No intervention