The Model for End-Stage Liver Disease Sodium (MELD-Na) Score in Non-cirrhotic Patients With Gastric Cancer

Istanbul Training and Research Hospital

Status: Completed

Conditions: Gastric Cancer; Morality; Complication,Postoperative; Complications; Gastrointestinal, Postoperative

Treatments: Other: MELD-Na score

Study type: Observational

Funder types: Other

Identifiers

NCT04791293

2630

Details and patient eligibility

About

Gastric cancer is the fifth most common cancer worldwide. Gastrectomy with lymphadenectomy is still the most effective treatment modality, depending on the stage and location. Despite many radiological, surgical and anesthetic innovations, serious complications such as anastomotic leakage, intra-abdominal abscesses, wound complications are seen secondary to gastrectomy. Many clinical studies have been conducted to prevent and predict these complications.

The Model for End-Stage Liver Disease (MELD) score, in which bilirubin, international normalized ratio (INR) and serum creatinine values were used to determine surgical risks in patients scheduled for liver transplantation. Latter developed by adding serum sodium (Na) to the formula. The MELD-Na score is used to predict postoperative complications in non-cirrhotic patients because of its simple and easy calculation.Moreover, The Meld-Na score was later used to predict complications for surgical procedures other than liver surgery such as colorectal surgery.

In this study, we aimed to investigate the importance of the Meld-Na score in predicting the perioperative and postoperative outcomes in patients with gastric cancer.

Enrollment: 159 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing gastrectomy due to gastric cancer

Exclusion criteria

• Patients with pulmonary, hepatic and renal disfunctions,
• Patients with diagnosed with a different cancer in the last 5 years and
• Pregnant patients

Trial design

159 participants in 2 patient groups

Group 1

Description:

Patients with postoperative complications

Treatment:

Other: MELD-Na score

Group 2

Description:

Patients without postoperative complications

Treatment:

Other: MELD-Na score