The Modulatory Effect of Oxytocin on Interoception

University of Electronic Science and Technology of China

Status

Completed

Conditions

Interoception

Treatments

Drug: oxytocin

Drug: placebo

Study type

Interventional

Funder types

Other

Identifiers

NCT03074409

UESTC-neuSCAN-34

Details and patient eligibility

About

This study is designed to investigate oxytocin's effects on interoception and whether these effects vary as a function of different emotional valence.

Full description

The present study will use a double-blind, between-subject, placebo-controlled design to investigate the modulatory effect of oxytocin on interoception and whether this effect will vary as a function of emotional valence. In Experiment 1, subjects will perform a heartbeat detection task and the group differences between oxytocin and placebo groups of the interoceptive accuracy and neural activity in the core interoceptive network will be investigated. In Experiment 2, subjects will be asked to watch emotional faces while perform the heartbeat detection task. Investigators will examine whether oxytocin's effects on interoception will be varied as a function of different emotional valence.

Enrollment

83 patients

Sex

Male

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Healthy subjects

Exclusion criteria

Subjects reported having any neurological problems, psychiatric illness or drug or alcohol abuse and none were currently taking any form of medication and had not drunk any caffeine-containing beverages on the day of the experiment.