The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

National Health Research Institutes, Taiwan

Status: Completed

Conditions: Tuberculosis

Study type: Observational

Funder types: Other

Identifiers

NCT00266383

DOH94-DC-1009

Details and patient eligibility

About

The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in the susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a 5-fold higher prevalence of tuberculosis than the Han Chinese. Whether genetic factors such as NRAMP 1 polymorphisms play a role in the prevalence of tuberculosis in Taiwanese aboriginals should be clarified.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• The NRAMP 1 polymorphism of tuberculous patients in Taiwan.

Exclusion criteria