The "Motoric Cognitive Risk" Syndrome in the Canadian Population (MCR-CardioV)

Jewish General Hospital

Status: Active, not recruiting

Conditions: Cognition Disorders in Old Age; Cardiovascular Diseases; Dementia

Treatments: Other: Summarize of participants' characteristics using means and standard deviations or frequencies and percentages

Study type: Observational

Funder types: Other

Identifiers

NCT03679026

CODIM-FLP-16 261

Details and patient eligibility

About

Cognition and locomotion are two human abilities controlled by the brain. Their decline is highly prevalent with aging, and is greater than the simple sum of their respective prevalence, suggesting a complex age-related interplay between cognition and locomotion. Recently, a systematic review and meta-analysis has provided evidence that poor gait performance predicts dementia and, in particular, has demonstrated that "motoric cognitive risk" (MCR) syndrome, which has been described in cognitively healthy individuals and combines subjective cognitive complaint with objective slow gait speed, is a pre-dementia syndrome. The uniqueness of "motoric cognitive risk" (MCR)syndrome is that it does not rely on a complex evaluation or laboratory investigations. Thus, it is easy to apply in population-based settings. The overall objective of the proposal is to examine the epidemiology of the newly reported "motoric cognitive risk" (MCR) syndrome, in the Quebec population using the database of the NuAge study.

Enrollment: 1,461 estimated patients

Sex: All

Ages: 45 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Individuals eligible for this study will be participants of the NuAge study

Exclusion criteria

• Individuals not eligible for the NuAge study
• dementia
• mobility disability
• no information about cognitive complaint
• no measure of walking speed

Trial design

1,461 participants in 2 patient groups

CVRF

Description:

individuals with cardio-vascular risk factors and diseases

Treatment:

Other: Summarize of participants' characteristics using means and standard deviations or frequencies and percentages

WCVRF

Description:

individuals without cardio-vascular risk factors and diseases

Treatment:

Other: Summarize of participants' characteristics using means and standard deviations or frequencies and percentages