The National Center for Testing Treatments in Chronic Spinal Cord and Traumatic Brain Injury (NCTT)

The University of Texas System (UT)

Status: Invitation-only

Conditions: Traumatic Brain Injury; Spinal Cord Injury

Treatments: Other: Data and sample repository

Study type: Observational

Funder types: Other

Identifiers

NCT02769416

HSC-MS-15-0705

Details and patient eligibility

About

The NCTT is a prospective, multicenter, observational research network for subjects with chronic spinal cord and/or chronic traumatic brain injury.

Full description

Current treatment for Spinal Cord Injury and Traumatic Brain Injury focuses on stabilizing the patient and preventing secondary injury with the aim of maximizing the best chance of recovery. Most patients will show varying amounts of recovery, but, when the injury is severe, that recovery is only partial. Enrollment in the NCTT will allow for classification and characterization of injury, function, co-morbidities, secondary issues/problems, research interests and will serve as a conduit for enrollment into interventional studies.

Enrollment: 5,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• History of spinal cord injury and/or brain injury
• Able to provide HIPAA authorization to share prior medical records/imaging
• Age 18 and older.

Exclusion criteria

• Life expectancy less than 6 months, vegetative state or co-existing disease or other characteristic that precludes appropriate diagnosis of spinal cord or brain injury.
• Other condition that, in the opinion of the site investigator, would interfere with adherence to study requirements.
• Inability or unwillingness of subject or legal guardian/representative to give informed consent (e.g., ward of the state).

Trial design

5,000 participants in 2 patient groups

Spinal Cord and Traumatic Brain Injury Subjects

Description:

Patients with a history of spinal cord and/or traumatic brain injury will provide data and samples so that they may be queried for interventional studies.

Treatment:

Other: Data and sample repository

Family Members and Healthy Volunteers

Description:

Healthy volunteer controls or family members may be enrolled for identification of genetic mutations.

Treatment:

Other: Data and sample repository