The Nature of Reflux-respiratory Symptoms Association in Difficult to Treat Wheezing\Coughing Babies

Wolfson Medical Center (WMC)

Status: Completed

Conditions: Wheezing; Asthma; Cough

Treatments: Device: WEEM - Wheezy Monitoring

Study type: Observational

Funder types: Other

Identifiers

NCT00512382

688 special

Details and patient eligibility

About

GER and respiratory symptoms are both common phenomenon in children. Both can coexist in the same patient by chance alone. Research reveals increased incidence for both to coexist leading to suspect a temporal association and possible causality. Therefore we conducted an observational study To determine the primary cause (RS or GER)using for the first time both PH-Impedance as measurements of GER and Wheezy monitoring (WEEM) that records simultaneously wheeze and cough noises. Both modalities will be recorded for 12-24 hours. If GER precedes cough/wheeze recordings it points to GER being the possible precipitating factor and vice versa.

Full description

GER and respiratory symptoms are both common phenomenon in children. Both can coexist in the same patient by chance alone. Research reveals increased incidence for both to coexist leading to suspect a temporal association and possible causality. Therefore we conducted an observational study To determine the primary cause (RS or GER)using for the first time both PH-Impedance as measurements of GER and Wheezy monitoring (WEEM) that records simultaneously wheeze and cough noises. Both modalities will be recorded for 12-24 hours. If GER precedes cough/wheeze recordings it points to GER being the possible precipitating factor.However, If cough/wheeze precedes GER recordings it points to cough/wheeze being the possible precipitating factor. The recordings will be investigated 1 minute before and one minute after each event.

Enrollment: 15 patients

Sex: All

Ages: 1 to 18 months old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Children 1 month - 18 years old
• Difficult to treat asthma
• Difficult to treat cough
• Difficult to treat other respiratory symptoms

Exclusion criteria

• Children on artificial ventilation
• Children not compliant with PH-Metria and/or WEEM

Trial design

15 participants in 2 patient groups

A

Description:

Babies and small children 1-24 months

Treatment:

Device: WEEM - Wheezy Monitoring

B

Description:

Children 2-18 years old

Treatment:

Device: WEEM - Wheezy Monitoring