The Number of Blastocysts Formed in the Outcome of Freeze All Strategy: COMFFETI Trial, Cumulative Delivery Rate

Assisting Nature

Status: Unknown

Conditions: Pregnancy, Ovarian

Treatments: Diagnostic Test: Pregnancy Rate

Study type: Observational

Funder types: Other

Identifiers

NCT03463278

Blastocyst-AN004

Details and patient eligibility

About

A prospective study of the blastulation rate in the outcome of the Freeze all strategy

Full description

A prospective study of the blastulation rate in women under the age of 40 years following Freeze all strategy, according to AMH levels and sperm parameters.

Study group 1: number of vitrified blastocysts 0-4 Study group 2: number of vitrified blastocysts 5-7 Study group 3: number of vitrified blastocysts >7

Enrollment: 160 estimated patients

Sex: Female

Ages: 20 to 39 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• primary infertility
• age 20-39 years;
• body mass index (BMI) 18-29kg/m2;
• regular menstrual cycle of 26-35days,
• presumed to be ovulatory;
• >1mil/ml spermatozoa;
• short antagonist protocol

Exclusion criteria

• poor responders;
• age ≥40;
• TESE sperm;
• PGS cycles;
• donor oocytes;
• donor sperm

Trial design

160 participants in 3 patient groups

0-4 blastocysts

Description:

group A: cumulative pregnancy rate of 0-4 blastocysts vitrified

Treatment:

Diagnostic Test: Pregnancy Rate

5-7 blastocysts

Description:

group B: cumulative pregnancy rate of 5-7 blastocysts vitrified

Treatment:

Diagnostic Test: Pregnancy Rate

>7 blastocysts

Description:

group C: cumulative pregnancy rate of \>7 blastocysts vitrified

Treatment:

Diagnostic Test: Pregnancy Rate