The Outcomes of Arteriovenous Fistula Cannulated From Different Direction.

Dongliang Zhang, MD

Status: Terminated

Conditions: Arteriovenous Fistula

Treatments: Other: Opposite direction cannulation; Other: Same direction cannulation

Study type: Interventional

Funder types: Other

Identifiers

NCT01642459

2012-0107

Details and patient eligibility

About

The investigators hypothesis that aneurysms and stenoses will be decreased if the direction of inserted arterial needle were same as the direction of blood flow, when compared to the opposite direction puncture.

Full description

Native arteriovenous fistula (AVF) is the preferred access for hemodialysis, and cannulation technique is very important factors affect the outcomes of AVF. Rope-ladder cannulation is one kind of the standard puncture techniques which is used commonly in maintenance hemodialysis (MHD) patients. There are many complications for rope-ladder cannulation, such as venous aneurysm and vascular stenosis, which may induce AVF dysfunction. For the venous outflow way, there always be aneurysm followed by stenoses at the sites of needle connected with the arterial line in rope-ladder cannulation patients. The investigators hypothesis that the directions of inserted arterial needles should affect the AVF outcomes. The present prospective study will compare the outcomes of AVF between the puncture direction at arterial needle sites same as blood flow and opposite to blood flow.

Enrollment: 10 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• MHD patients with autogenous AVF.
• Newly setup AVF in 3 months.
• Fore- or Upper arm AVF.
• Flow of >800ml/min detected by using the ultrasound dilution technique.

Exclusion criteria

• AVF after neoplasty.
• Arteriovenous grafts.
• Anticipated live time less than one year.
• Patients whose concurrent illnesses, disability, or geographical residence would hamper attendance at required study visit.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

Same direction cannulation

Experimental group

Description:

The inserted direction of arterial needle is same as the direction of blood flow.

Treatment:

Other: Same direction cannulation

Opposite direction cannulation

Active Comparator group

Description:

The inserted direction of arterial needle is opposite to the direction of blood flow.

Treatment:

Other: Opposite direction cannulation