ClinicalTrials.Veeva

Menu

The Patients' Experience After Stem Cell Transplant

University of Nebraska logo

University of Nebraska

Status

Completed

Conditions

Stem Cell Transplant Complications

Study type

Observational

Funder types

Other

Identifiers

NCT03454568
0431-17-EP

Details and patient eligibility

About

This study will examine how adults ≥ 60 years old thinking and memory abilities are affected by stem cell transplant; whether these changes affect day-to-day activities and quality of life and how thinking and memory abilities are affected by genetics, depression, anxiety and physical function. Genetics and other factors may affect the brain's chemicals or structure, and may increase risk for negative effects on thinking and memory.

Full description

In this study, the investigators are looking to understand: 1) how adults ≥ 60 years old thinking and memory abilities are affected by stem cell transplant; 2) whether these changes affect day-to-day activities and quality of life; and 3) how thinking and memory abilities are affected by genetics, depression, anxiety and physical function. Genetics and other factors may affect the brain's chemicals or structure, and may increase risk for negative effects on thinking and memory. Participants will undergo neurocognitive testing along with the collection of a saliva sample and completing a battery of questionnaires and assessments.

Enrollment

110 patients

Sex

All

Ages

60 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Between the ages of 60-85
  2. Diagnosed with a hematological malignancy
  3. Is considering an autologous or allogeneic stem cell transplant OR has undergone stem cell transplant in the past 12 months and seen by the PI for pre-transplant evaluation.
  4. Is able to read, write, speak, and understand English

Exclusion criteria

  1. As per self report or medical record, history of central nervous system involvement and/or history of cranial irradiation or intrathecal chemotherapy except for patients with history of prophylactic intrathecal chemotherapy.
  2. As per self report or medical record, history of stroke, head injury, neurosurgery, seizure disorder, or demyelinating disorder.
  3. As per self report or medical record, history of substance use disorder.
  4. As per self report or in the judgement of the consenting professional, uncorrected vision loss.
  5. As per self report or medical record, primary psychiatric disorder necessitating inpatient treatment in the last 12 months.
  6. As per self report or medical record, history of allogeneic and or autologous stem cell transplant.

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems