The Perioperative Value of Platelet Counts in Predicting Outcome After Liver Transplantation

University of Zurich (UZH)

Status: Unknown

Conditions: Death; Complication

Treatments: Procedure: Liver transplantation

Study type: Observational

Funder types: Other

Identifiers

NCT01711957

EK-1487

Details and patient eligibility

About

Recent experimental and clinical studies have shown that platelets play a critical role in liver ischemia and regeneration. Thrombocytopenia, a frequent and potentially serious condition in liver transplantation (LT) recipients, was shown to be associated with postoperative morbidity and mortality after partial hepatectomy.

The investigators aim at evaluating whether postoperative low platelet counts are indicators of short- and long-term outcomes after liver transplantation.

Enrollment: 250 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >18 years old
• End stage liver disease
• Cadaveric-donor liver transplantation

Exclusion criteria

• Age <18 years old
• Pregnancy
• Living-related liver transplantation

Trial design

250 participants in 1 patient group

Liver disease and liver transplantation

Description:

Patient with end stage liver disease and/or primary liver tumor undergoing liver transplantation

Treatment:

Procedure: Liver transplantation