The Perspective of Healthy Individuals on Breast Cancer Risk Prediction Report In The Indonesian Population (PERCEPTION)

Nalagenetics

Status: Completed

Conditions: Breast Cancer

Treatments: Other: Focus Group Discussion

Study type: Interventional

Funder types: Industry; Other

Identifiers

NCT05562440

ID-BCRPS-02-20220913

Details and patient eligibility

About

In 2016, a meta-analysis showed that DNA-based risk reporting alone does not facilitate behavior change. However, there have been several studies showing that tailoring care plans related to diet may help with adherence to a tailored diet plan.

Risk prediction report displays both Polygenic Risk Score (PRS) and modifiable (non-genetic) risk factors. Overtime, the investigators aim to combine both PRS and modifiable risk factors to have a localized and stronger prediction model for the local population. The risk prediction report is designed to tailor care plans for patients by their physicians or care planner.

Focus groups allow deeper discussions in themes important to guide design of the report. This method has been used in previous similar studies, such as one by Cutting et al to understand physicians' preference in integrating genetic reports into daily practice. Studies also have shown that local adoption of personalized medicine and care is hindered by limited infrastructure of information management and awareness, despite personalized medicine being widely adopted in healthcare systems in developing countries.

Enrollment: 10 patients

Sex: Female

Ages: 25 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Female
2. Able to give informed consent
3. Aged 25-75 years old
4. Have access to a mobile phone or computer with the Zoom application or a caregiver who is able to assist them with the Zoom application

Exclusion criteria

1. Ever diagnosed with breast cancer

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Focus Group Discussion on breast cancer risk prediction report

Experimental group

Description:

Woman population with no breast cancer who received the dummy report result

Treatment:

Other: Focus Group Discussion