The Physical Exercise and Prostate Cancer Study (PEPC)

University of Oslo (UIO)

Status and phase: Completed; Phase 3

Conditions: Prostate Cancer

Treatments: Behavioral: Strength training group

Study type: Interventional

Funder types: Other

Identifiers

NCT00658229

REK - 08/212b

Details and patient eligibility

About

The purpose of this study is to determine the effectiveness of a four months strength training program on physical and psychological health in patients with prostate cancer during androgen deprivation therapy. It is hypothesized a beneficial effect of the intervention on physical and psychological health in patients with prostate cancer treated with androgen deprivation.

Enrollment: 60 patients

Sex: Male

Ages: Under 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Newly diagnosed locally advanced prostate cancer (clinical stage T2 and T3)
• Referred to RH and UUS for radiotherapy
• < 75 years
• Capable of reading and writing Norwegian
• Treating oncologist must approve of the subjects' participation
• Living within approximately 1 hour from Oslo by car or public transportation

Exclusion criteria

• Routinely resistance training with manuals
• Medication for osteoporosis (i.e. bisphosphonates)
• Conditions of a severity that contraindicate exercise without adjusted actions
• Mentally incompetent conditions
• Conditions of a severity that complicates the ability to participate in a supervised training program

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Strength training group

Experimental group

Description:

A four months strength training program during androgen deprivation therapy for prostate cancer patietns.

Treatment:

Behavioral: Strength training group

Control group

No Intervention group

Description:

Patients in the control group are not discouraged from performing normal activities. They are however asked not to start a strength training program or increase their activity level in the same period as the experimental group is performing their strength training program. We will offer the control group a modified strength training program after the post-intervention assessment.