The Platinum Study Comparison Group

Lawrence Einhorn

Status

Completed

Conditions

Testicular Neoplasms

Treatments

Behavioral: Questionnaire

Study type

Observational

Funder types

Other

Identifiers

NCT02890030

IRB No. 1604502652

Details and patient eligibility

About

The patients enrolled on this new study will serve as an appropriate comparison group consisting of patients with the diagnosis of germ cell testicular cancer who were cured with surgical resection and did not receive cisplatin-based chemotherapy with a group of patients from another study who did receive cisplatin-based chemotherapy.

Full description

Primary Objective

To compare the prevalence of ototoxicity and neurotoxicity in GCT cancer survivors who only had surgery to a similar population from The Platinum Study (RSRB45410/1305011509) who received cisplatin-based combination chemotherapy.

Secondary Objective

To compare the prevalence of obesity, hypertension, and use of antidepressants/anxiolytics in GCT cancer survivors who only had surgery to a similar population from The Platinum Study who received cisplatin-based combination chemotherapy.

Enrollment

102 patients

Sex

Male

Ages

18 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Diagnosis or confirmation of diagnosis of a histologically or serologically confirmed testicular germ cell tumor (GCT) or GCT at another anatomic location
Age at GCT diagnosis: 55 years of age or younger
Males, 18 years of age or older at time of study consent
Subject is able to provide consent
Subject is able to speak and read English
Treatment consisted of surgery only (i.e., orchiectomy and/or retroperitoneal lymph node dissection [RPLND]) for either initial testicular germ cell tumor (GCT) or subsequent testicular cancer
Subject completed surgery > 1 year ago
Subject is currently undergoing active follow-up at IU
Subject did not require any subsequent chemotherapy, salvage chemotherapy treatment or bone marrow transplant.
Subject had no prior chemotherapy of any kind