The Potential Role Of MicroRNA-155 And Telomerase Reverse Transcriptase In Diagnosis Of Non-Muscle Invasive Bladder Cancer And Their Pathological Correlation

Mansoura University

Status: Completed

Conditions: Bladder Cancer; Bladder Neoplasm; Micro-RNA; Bladder Disease

Treatments: Diagnostic Test: Human telomerase reverse transcriptase; Diagnostic Test: MicroRNAs-155

Study type: Interventional

Funder types: Other

Identifiers

NCT03591367

MicroRNA-155 Bladder Cancer

Details and patient eligibility

About

We try to assess the potential role of telomerase reverse transcriptase and MicroRNA (miR-155) in diagnosis of non-muscle-invasive bladder cancer and their correlation with stage and grade of the tumor.

Enrollment: 115 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Men and women 18 years or older.
• Patient with hematuria suspected to be of bladder origin clinically.
• Willing to be participate in the study.

Exclusion criteria

• Patient having another malignancy.
• Hematuria of other causes as trauma and stones

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

115 participants in 1 patient group

Hematuria due to suspicious superficial bladder tumor

Other group

Description:

MicroRNAs-155 (miRNAs-155) and Human telomerase reverse transcriptase (hTERT)

Treatment:

Diagnostic Test: MicroRNAs-155

Diagnostic Test: Human telomerase reverse transcriptase