The Precision of Pulmonary Artery Cardiac Output-measurements in Spontaneously Breathing Patients (TEMP2)

Norwegian University of Science and Technology

Status: Completed

Conditions: Heart Diseases

Treatments: Procedure: Cardiac output measurement at random to respiration; Procedure: Cardiac output measurement timed to instructed exhalation; Procedure: Cardiac output measurement synchronised at start of expiration

Study type: Interventional

Funder types: Other

Identifiers

NCT01944254

2013/409

Details and patient eligibility

About

The intention of this study is to determine whether the precision of the measure of cardiac output can be optimized by conducting the measurement while the participant is instructed to exhale slowly. This will be compared to measurements done at random to respiration and timed with the participant's spontaneous expiration.

Enrollment: 18 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Every patient that receives a pulmonary artery catheter (PAC) related to elective cardiac surgeries,
• informed and written consent to participation in the study in accordance with the Helsinki declaration
• hemodynamic stability

Exclusion criteria

• Hemodynamical instability
• atrial fibrillation
• tricuspid insufficiency ≥ grade 2
• hemodialysis or other conditions where extra volume load can be negative,
• lack of ability to give a written consent to participate in the study

Trial design

18 participants in 3 patient groups

random to respiration

Active Comparator group

Description:

Cardiac output measurement at random to respiration

Treatment:

Procedure: Cardiac output measurement at random to respiration

timed with expiration start

Experimental group

Description:

Cardiac output measurement synchronised at start of expiration.

Treatment:

Procedure: Cardiac output measurement synchronised at start of expiration

timed to instructed exhalation

Experimental group

Description:

Cardiac output measurement timed to instructed exhalation. The patient will receive instructions to exhale slowly using a peak expiratory flow (PEF)-flute and the cardiac output measurement will be started (i.e bolus given) at the start of expiration.

Treatment:

Procedure: Cardiac output measurement timed to instructed exhalation