The Predictive Scores for Gastric Cancer in Gastric Intestinal Metaplasia (GIM) Patient: a Recommendation for Thai Population

King Chulalongkorn Memorial Hospital

Status: Unknown

Conditions: Gastric Intestinal Metaplasia

Study type: Observational

Funder types: Other

Identifiers

NCT01490541

RP003

Details and patient eligibility

About

The predictive scores for gastric cancer in gastric intestinal metaplasia(GIM) patient: a recommendation for Thai population.

Objective:

To evaluate major risk factors for gastric cancer in gastric intestinal metaplasia(GIM) patient in order to propose the appropriate recommendation for Thai people.

Research Design:

Single center, retrospective-cohort study.

Full description

Study population and Sample size at Faculty of Medicine, Chulalongkorn University The patients who were diagnosed gastric intestinal metaplasia from 1997 to 2012 and then follow up for 5 years. Estimate sample size =280

• Investigational product, dosage & route of administration
• Questionnaire for explore the risk factors
• EGD with biopsy
• Blood sampling for gastro panel
• Duration of participation
• 5 years or until diagnose gastric cancer

Statistical method:

Unconditional-binary-logistic regression

Enrollment: 280 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. All patients were diagnosed GIM
2. All patients have to sign the consent form

Exclusion criteria

1. Previous gastric surgery including gastrectomy and bypass surgery
2. Bleeding tendency including decompensated cirrhosis, chronic kidney disease and long-tem antiplatelets or anticoagulants
3. HIV infection
4. History of proton pump inhibitor use within 1 week
5. History of antibiotic use within 4 weeks

Trial design

280 participants in 1 patient group

Gastric intestinal metaplasia patient