The Prenatal/Early Infancy Project: An Adolescent Follow-up

University of Colorado Denver (CU Denver)

Status: Completed

Conditions: Behavior, Adaptive

Treatments: Behavioral: Screening, Transport, Prenatal Visits; Behavioral: Developmental Screening; Behavioral: Screen, Transport, Prenatal/Inf Visits; Behavioral: Screening plus Transportation

Study type: Interventional

Funder types: Other

Identifiers

NCT03079752

UColorado

Details and patient eligibility

About

The Nurse-Family Partnership, a program of prenatal and infancy home visiting by nurses, has been examined in a series of 3 randomized trials since 1977. It has received considerable attention in the scientific and public policy communities for its replicated effects on a variety of maternal and child health outcomes across these 3 trials, including prenatal health, childhood injuries, rates of subsequent pregnancies, inter-birth intervals, as well as its long-term effects on maternal life-course, criminal behavior, and 15-year-olds' criminal and antisocial behavior in the first trial of the program conducted in Elmira, New York.

Full description

Although this program produced positive effects on maternal and child health from pregnancy through the child's fourth year of life, its long-term effects remain unexamined. The current study was conducted to determine the extent to which the beneficial effects of the program set in motion early in the life cycle altered the life-course trajectories of the mothers and the children's adaptive functioning through the first child's 15th birthday. This study examines the long-term effects of the program on two domains of maternal functioning: 1) maternal life course (subsequent children, use of welfare, employment, substance abuse, and encounters with the criminal justice system); and 2) perpetration of child abuse and neglect; and two domains of the children's behavior: 1) their functioning in schools, and 2) their criminal and antisocial behavior. The investigators hypothesized that the program effects in these domains of maternal and child functioning, as in earlier phases of the study, would be greater for families in which the mothers experienced a larger number of chronic stressors and had fewer resources to manage the challenges of living in poverty and being a parent.

Enrollment: 629 patients

Sex: All

Ages: 15+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: Must be offspring of mothers who enrolled in Elmira randomized clinical trial of the Nurse-Family Partnership (known as the Prenatal Early Infancy Project) -

Exclusion Criteria:

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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629 participants in 4 patient groups

Developmental Screening

Active Comparator group

Description:

Participants received sensory and developmental screening and referral for further evaluation and treatment of suspected problems at 12 and 24 months of age.

Treatment:

Behavioral: Developmental Screening

Screening plus Transportation

Active Comparator group

Description:

Participants received sensory and developmental screening and referral for further evaluation and treatment of suspected problems at 12 and 24 months of age; their mothers received free transportation for regular prenatal and well-child care (through child age two).

Treatment:

Behavioral: Screening plus Transportation

Behavioral: Developmental Screening

Screening, Transport, Prenatal Visits

Active Comparator group

Description:

Participants received sensory and developmental screening and referral for further evaluation and treatment of suspected problems at 12 and 24 months of age; their mothers received free transportation for regular prenatal and well-child care (through child age two), plus nurse home visiting during pregnancy.

Treatment:

Behavioral: Screening plus Transportation

Behavioral: Screening, Transport, Prenatal Visits

Behavioral: Developmental Screening

Screen, Transport, Prenatal/Inf Visits

Experimental group

Description:

Participants received regular sensory and developmental screening and referral for further evaluation and treatment of suspected problems at 12 and 24 months of age; their mothers received free transportation for regular prenatal and well-child care (through child age two), plus nurse home visiting during pregnancy and through child age two.

Treatment:

Behavioral: Screening plus Transportation

Behavioral: Screening, Transport, Prenatal Visits

Behavioral: Screen, Transport, Prenatal/Inf Visits

Behavioral: Developmental Screening