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The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache

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FARO T. OWIESY, M.D

Status

Completed

Conditions

Cluster Headache
Craniofacial Pain Syndrome

Treatments

Other: Minimal surgical exploration for a neuroma

Study type

Observational

Funder types

Other

Identifiers

NCT04845451
CoronaDMC

Details and patient eligibility

About

Role of a neuroma of zygomatic-temporal in triggering of a cluster headache. Exploratory diagnosis, resection, and pathological examination of tumor anticipated

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Full description

An anatomical coordinated communication of a Cluster Circuit turned on by Zygomatico-Temporal neuroma, a malicious possibly nontraumatic, neoplastic tissue coding and decoding itself upon autonomic release of neurotransmitter(s). Exhaustion of neurotransmitter synthesis turns out the explosions of pain-symptoms off.

Poor attention to the characterization of a peripheral neuroma of trigeminal nerve branch deranged attention to central(CNS) characterization of Cluster Symptoms.

This study based on our experimental results of minimal surgical procedure to explore, diagnose and resect a Zygomatico-Temporal neuroma in the temple of patients suffering from EpisodicChronic, Cluster Headache-ECCH. The goal is to light on this speculation in a novel analysis of events to put an end to devastating catastrophic headaches. Detailed anatomical components loci of the autonomic symptoms in the cluster headache reveal the presence of an electrical neural circuit.

The extracranial circuit components of ECCH reflects the anatomical nerve components participating reflection of the single circumscribed symptom:

  1. Zygomatico-Temporal-neuroma
  2. Zygomatic nerve V-II
  3. Intraorbital communicants rami
  4. Lacrimal nerve V-I
  5. Ophthalmic nerve Intraorbital routing, supraorbital nerves, the upper eyelid, the conjunctiva and cornea of the eye, the nose (including the tip of the nose, except alae nasi), the nasal mucosa, the frontal sinuses. V-I
  6. Optic nerve via ophthalmic nerve routing and electricity propagation.
  7. Pterygopalatine ganglion as peripheral and CNS coordinator center.

An intracranial CNS reaction follows in response to the perception of pain materialized in neuroimaging during the activity of ECCH.

Enrollment

5 patients

Sex

All

Ages

20 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Cluster headache

Exclusion criteria

  • Malignant hypertension,
  • Brain tumors,
  • Cerebral vascular abnormalities,
  • Presence of a brain or nerve electro stimulator.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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