The Presence of Microbes in the Sperm and Their Impact on Sperm Capacitation and IVF Treatment

Clalit Health Services

Status: Unknown

Conditions: Infertility

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT02585297

Meir hospital

Details and patient eligibility

About

Study Goals:

1. Finding the prevalence of bacteria of the sperm in an innovative and more accurate methode
2. Understanding the effect of microbes on the process of capacitation
3. The impact of microbes in the sperm on IVF success rate
4. Finding the incidence of vaginal bacteria and their relationship to bacteria of the sperm
5. The impact of vaginal flora on IVF success rate

Full description

Prospective non interventional study in the Department of Life Sciences, Bar-Ilan University and IVF Unit at Meir Hospital.

The control group consisting of 50 semen samples from men with no sperm problems and 50 vaginal samples from their partners.

The study group consisting of 50 semen samples from men with male fertility problems and 50 vaginal samples from their partners.

The semen taken from the remains after fertilization of the IVF laboratory. (Liquid otherwise routinely thrown).

Vaginal samples taken from women undergoing IVF treatment under anesthesia after informed consent.

Enrollment also collect the following data: age, race, chronic illnesses, past surgeries and former fertility treatments. Data will be collected through anamnesis of the patient or the medical file after consent.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male and female undergoing fertility treatments

Exclusion criteria

• Male and female not undergoing fertility treatments

Trial design

200 participants in 4 patient groups

Control- semen

Description:

Semen of fertile men

Treatment:

Other: no intervention

Control- vaginal discharge

Description:

Vaginal discharge of partners of fertile men

Treatment:

Other: no intervention

Case-semen

Description:

Semen of infertile men

Treatment:

Other: no intervention

Case- vaginal discharge

Description:

Vaginal discharge of partners of infertile men

Treatment:

Other: no intervention