The Prevalence and Characteristics of Adrenal Incidentaloma

Chongqing Medical University

Status: Completed

Conditions: Prevalence; Adrenal Incidentaloma

Study type: Observational

Funder types: Other

Identifiers

NCT04682938

AI-China2020

Details and patient eligibility

About

To investige the prevalence, characteristics and prognosis of adrenal incidentalomas in Chinese adults.

Full description

With the development of imaging detection technology and its wide application in clinic, the detection rate of adrenal incidentaloma (AI) has been greatly improved. Most AI are benign and do not have the function of autonomic hormone secretion, but about 20% of them have function and can secrete adrenal hormone autonomously. Studies based on biopsy reports show that the prevalence of AI is about 2%, and the prevalence of AI detected by CT scan is 1% - 4.5%. However, most of these studies are retrospective, and there may be selection bias and other confounding factors. There is no large sample prospective study on the prevalence of AI in the general population. The purpose of this study is to prospectively include patients with adrenal incidentaloma in community physical examination population, and evaluate their function and prognosis. The research results will provide new evidence for standardized diagnosis and treatment of adrenal incidentaloma in the future.

Enrollment: 25,356 patients

Sex: All

Ages: 18 to 78 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

·On weekdays, the first 100 individuals, aged 18 to 78 years, taking health checkup in the Community Health Examination Center were invited to take part in the study.

Exclusion criteria

• with known adrenal diseases;
• with continuous steroids or drug treatment that might influence cortisol secretion ordexamethasone metabolism and could not be stopped
• refuse to participate in the study.

Trial design

25,356 participants in 1 patient group

adrenal incidentalomas in Chinese community adults

Description:

On weekdays, the first 100 individuals, aged 18 to 78 years, taking health checkup in the Community Health Examination Center were invited to take part in the study.