The Prevalence and Risk Factors for Thyroid Dysfunction in Pregnant Women in Taiwan

Chang Gung Medical Foundation

Status: Unknown

Conditions: Thyroid Disease Pregnancy

Treatments: Drug: PTU 50 MG Oral Tablet; Drug: Levothyroxin

Study type: Observational

Funder types: Other

Identifiers

NCT04936698

202100365B0

Details and patient eligibility

About

The investigators' aim is to enroll around 2000 patients from Taipei, Keelung, Linkou, Chiayi and Kaohsiung CGMH. All participants will receive universal thyroid function screening at 1st trimester, and those who was found to have hyperthyroidism or hypothyroidism will be referred to Endocrine department for further treatment. All participants will be followed at outpatient clinic, and their obstetric visit finding will be recorded. The maternal and neonatal outcomes will be analyzed.

Enrollment: 2,000 estimated patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women at first trimester (< 14 weeks of gestational age)

Exclusion criteria

• None

Trial design

2,000 participants in 3 patient groups

Hyperthyroidism

Description:

Elevated fT4, low TSH

Treatment:

Drug: PTU 50 MG Oral Tablet

Hypothyroidism

Description:

Elevated TSH, low fT4

Treatment:

Drug: Levothyroxin

Euthyroid

Description:

Normal TSH/fT4 level