the Prevalence of "Wearing-off" in Patients With Parkinson's Disease in Shanghai (shapd-woq)

Shanghai Jiao Tong University

Status: Completed

Conditions: Wearing Off Effect; Parkinson Disease

Treatments: Diagnostic Test: Wearing-off 9 questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT03792204

XH-18-011

Details and patient eligibility

About

The study would be designed as a multi-center cross-sectional investigation on the prevalence of Wearing-off in Parkinson's patients in Shanghai as well as related influencing factors.

Full description

PD patients would be randomly recruited into this investigation from around thirty hospital covering the 16 districts of Shanghai. The wearing off would be defined by two methods: the doctors' judgement or the WOQ-9 questionnaire which was a patient-determining tool. The investigation also includes the medicine, the severity of PD symptoms, the demographic factors. The study would be designed with the purpose of clarifying the prevalence of the "wearing-off" and its related influencing factors.

Enrollment: 1,480 patients

Sex: All

Ages: 35 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• have been clinical diagnosed with Parkinson's disease
• have received stable anti-Parkinson's treatment before being recruited to the study.

Exclusion criteria

• being suspicious of atypical Parkinson syndrome or secondary Parkinson syndromes
• have not received anti Parkinsonian treatment.
• being combined with serious cognitive dysfunction or psychiatric symptoms
• unable to complete the investigations.

Trial design

1,480 participants in 1 patient group

PD patients with wearing-off effect

Description:

people who have been clinically diagnosed with Parkinson's disease (PD) and have received anti PD therapy would be recruited into the study. The anti -PD treatment would not be changed in the population of the participants. We would use the tool of 'Wearing-off 9 questionnaire' to determine the prevalence of Wearing-off phenomenon in Parkinson's patients in Shanghai

Treatment:

Diagnostic Test: Wearing-off 9 questionnaire