The Prognosis Effect of Indocyanine Green (ICG) Fluorescence Guided Surgery on Disease-free Survival (DFS) of Stage III Colorectal Cancer

Shanghai Jiao Tong University

Status

Not yet enrolling

Conditions

Colorectal Cancer Stage III

Study type

Interventional

Funder types

Other

Identifiers

NCT06583564

2024-038-01

Details and patient eligibility

About

Previous studies of Indocyanine green (ICG) in colorectal surgery have focused on lymphatic mapping, lymph node detection, and the number of harvested lymph nodes. However, relatively few studies have evaluated the outcomes of this imaging technology, especially the prognosis following of colorectal cancer resection. The present study assessed the prognosis of stage III colorectal cancer patients following ICG fluorescence-guided surgery as compared to conventional surgery without the use of ICG Fluorescence imaging

Enrollment

192 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

age > 18 years,
confirmed diagnosis of primary CRC,
preoperative tumor stage of cT1 to cT4, N+, M0 as determined by contrast-enhanced computed tomography (CT),
no distant metastasis, and
American Society of Anesthesiologists(ASA)Physical Status Classification score of 1, 2, or 3

Exclusion criteria

history of previous colorectal surgery, emergent surgery, or palliative resection;
pregnancy or breastfeeding;
allergy or history of an adverse reaction to ICG
severe mental disorder.