The Prognostic Impact of Right Ventricular Systolic Dysfunction on the Survival of Patients With Sepsis and Septic Shock

Burapha University

Status: Completed

Conditions: Sepsis and Septic Shock

Study type: Observational

Funder types: Other

Identifiers

NCT06193109

Burapha university

Details and patient eligibility

About

This study sought to evaluate the association of right ventricular systolic dysfunction and 28-day in-hospital mortality in patients with sepsis and septic shock. Prospective cohort study of adult patients admitted at Burapha university hospital from October 1, 2022 through June 30, 2023 for sepsis and septic shock, who had an echocardiogram within 72 hours after admission for evaluating right ventricular systolic function. Right ventricular systolic dysfunction was defned by the American Society of Echocardiography criteria. Outcomes included 28-day in-hospital mortality, maximal blood lactate, length of intensive care unit(ICU) stay and duration of mechanical ventilation.

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• aged 18 years or older
• diagnosed with sepsis or septic shock according to Sepsis-3 criteria
• received an echocardiogram within 72 hours after admission

Exclusion criteria

• prior diagnosis of pulmonary hypertension,
• cor-pulmonale,
• significant valvular heart disease,
• acute coronary syndrome,
• aortic dissection,
• heart failure
• inability to follow up within 28 days

Trial design

200 participants in 1 patient group

the patients with sepsis or septic shock

Description:

devide two groups : (1) They had right ventricular dysfunction and (2) They had no right venticular dysfunction.