The Prognostic Role of Tricuspid Annular Plane Systolic Excursion in Critically Ill Patients With Septic Shock

Alexandria University

Status: Completed

Conditions: Septic Shock

Treatments: Radiation: tricuspid annular plane systolic excursion (TAPSE)

Study type: Observational

Funder types: Other

Identifiers

NCT06008067

TAPSESEPTIC

Details and patient eligibility

About

The aim of this study is to evaluate the possible prognostic performance of RV dysfunction, as assessed by TAPSE, in non-cardiac patients with septic shock.

Full description

The objective is to investigate the prognostic performance of right ventricular dysfunction, as assessed by tricuspid annular plane systolic excursion (TAPSE), in non-cardiac patients with septic shock.

Enrollment: 100 patients

Sex: All

Ages: 18 to 64 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (18 - 64 years old) with septic shock after admission according to 2016 consensus definition (Sepsis-3).

Exclusion criteria

• Pregnant females
• Trauma
• Documented coronary heart disease
• History of myocardial infarction
• Myocarditis
• Thrombo-embolic pulmonary disease
• Valvular heart disease
• Corpulmonale
• Arrhythmia
• Known left ventricular ejection fraction < 40%
• Poor echocardiographic window

Trial design

100 participants in 2 patient groups

Survivors

Description:

Patients who survived after day 28.

Treatment:

Radiation: tricuspid annular plane systolic excursion (TAPSE)

Non-survivors

Description:

Patients who died at or before day 28.

Treatment:

Radiation: tricuspid annular plane systolic excursion (TAPSE)