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The Prognostic Value of PET/CT for Tumor Progression in Patients With Metastatic Hormone-sensitive Prostate Cancer

Sun Yat-sen University logo

Sun Yat-sen University

Status

Completed

Conditions

PET / CT
Prostate Cancer Metastatic Disease

Study type

Observational

Funder types

Other

Identifiers

NCT06915714
IIT-2025-117

Details and patient eligibility

About

Investigators retrospectively collected data from consecutive patients treated at the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, from October 2020 to March 2024. The inclusion criteria were as follows: (1) patients with diagnosis of metastatic hormone-sensitive prostate cancer, confirmed by PSA levels, radiographic tests and pathological information; (2) patients who underwent FDG and PSMA PET/CT prior to the initiation of medical treatment. The exclusion criteria were as follows: (1) patients who received novel hormone therapy or a prostate biopsy prior to PET/CT; (2) patients with other malignancies; (3) patients received hormone therapy without NHT; (4) patients received chemotherapy or radiotherapy prior to or during novel hormone therapy; (5) absence of follow-up data at the hospital.

Enrollment

45 patients

Sex

Male

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients with diagnosis of metastatic hormone-sensitive prostate cancer, confirmed by PSA levels, radiographic tests and pathological information
  • patients who underwent FDG and PSMA PET/CT prior to the initiation of medical treatment

Exclusion criteria

  • patients who received novel hormone therapy or a prostate biopsy prior to PET/CT
  • patients with other malignancies
  • patients received hormone therapy without novel hormone therapy
  • patients received chemotherapy or radiotherapy prior to or during novel hormone therapy
  • absence of follow-up data at our institution

Trial design

45 participants in 4 patient groups

Group1
Description:
PCa40%MTV-P = High, PCa40%MTV-G = Low
Group2
Description:
PCa40%MTV-P = Low, PCa40%MTV-G = High
Group3
Description:
PCa40%MTV-P = Low, PCa40%MTV-G = Low
Group4
Description:
PCa40%MTV-P = High, PCa40%MTV-G = High

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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