The Prognostic Value of Tertiary Lymphatic Structure in Esophageal Squamous Cell Carcinoma

Tianjin Medical University

Status: Completed

Conditions: Esophageal Squamous Cell Carcinoma

Treatments: Other: no-Intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06241066

bc2023192

Details and patient eligibility

About

Retrospective analysis of the presence and maturity of tertiary lymphoid structures in pathological sections of patients with esophageal squamous cell carcinoma after surgical treatment. Pay attention to the overall survival and disease free survival of these esophageal squamous cell carcinoma patients.

Enrollment: 359 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Pathologically diagnosed as esophageal squamous cell carcinoma; 2. Surgery for esophageal cancer; 3. Complete medical records;

Exclusion criteria

• Patients with a previous history of malignant tumor

Trial design

359 participants in 4 patient groups

Surgery alone group

Description:

Patients who were diagnosed with esophageal squamous cell carcinoma and underwent esophageal squamous cell carcinoma resection without any prior treatment are included in this group. These patients had not been diagnosed with any other cancer. Finally, 96 patients were included.

Treatment:

Other: no-Intervention

Neoadjuvant chemotherapy group

Description:

Patients who were diagnosed with esophageal squamous cell carcinoma and underwent esophageal squamous cell carcinoma resection, and underwent routine chemotherapy before surgery were included in this group. These patients were not diagnosed with any other cancers Finally, 89 patients were included.

Treatment:

Other: no-Intervention

Neoadjuvant chemotherapy combined with immunotherapy group

Description:

Patients who were diagnosed with esophageal squamous cell carcinoma and underwent esophageal squamous cell carcinoma resection, and underwent routine chemotherapy combined with immunotherapy before surgery were included in this group. These patients were not diagnosed with any other cancers Finally, 81 patients were included.

Treatment:

Other: no-Intervention

Neoadjuvant chemotherapy combined with radiotherapy group

Description:

Patients who were diagnosed with esophageal squamous cell carcinoma and underwent esophageal squamous cell carcinoma resection, and underwent routine chemotherapy combined with radiotherapy before surgery were included in this group. These patients were not diagnosed with any other cancers Finally, 93 patients were included.

Treatment:

Other: no-Intervention