The Prophylactic Effect of Garlic Tablets to Prevent Nosocomial Infections in Intensive Care Unit Patients.

Alexandria University

Status and phase: Invitation-only; Phase 3

Conditions: Nosocomial Infection

Treatments: Drug: Garlic powder standardized to allicin

Study type: Interventional

Funder types: Other

Identifiers

NCT06833125

0108752

Details and patient eligibility

About

The goal of this clinical trial is to learn if garlic tablets works to prevent nosocomial infections in hospitalized patients in ICU. The main questions it aims to answer are:

Does garlic tablets administration lower the occurence of nosocomial infections in hospitalized patients in ICU?

Enrollment: 62 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients aged from 18 to 65 years old admitted to intensive care units without any type of infection.

Exclusion criteria

1. Patients with signs /symptoms of infection.
2. Patients with human immunodeficiency virus, malignancy and patients with a history of recent immunosuppressants or corticosteroids administration.
3. Patients with bleeding disorders or abnormal coagulation profile
4. Patients who will planned for surgery within 2 weeks.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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62 participants in 2 patient groups

The intervention group

Experimental group

Description:

The patients in the intervention group which will receive garlic tablets (Tomex plus 300 mg) two tablets twice daily for 6 days just after ICU admission

Treatment:

Drug: Garlic powder standardized to allicin

The control group

No Intervention group

Description:

The patients in the control group which will not receive the garlic tablets.