The PROspective German NOn-CF bronchiectaSIS Patient Registry (PROGNOSIS)

Hannover Medical School (MHH)

Status: Unknown

Conditions: Bronchiectasis

Study type: Observational

Funder types: Other

Identifiers

NCT02574143

PROGNOSIS

Details and patient eligibility

About

The purpose of this study is to study the epidemiology of non-CF bronchiectasis (NCFB) and to provide an estimate of the distribution (prevalence) of NCFB etiologies across all different levels of health care as well as real-life data regarding the current management of NCFB in Germany.

Full description

• To study the epidemiology of non-CF bronchiectasis (NCFB) and to provide an estimate of the distribution (prevalence) of NCFB etiologies across all different levels of health care as well as real-life data regarding the current management of NCFB in Germany
• To establish feasible investigational strategies in order to establish the etiology of NCFB
• To perform observational research into bronchiectasis, particularly in areas where single center datasets are underpowered, such as in rare etiologies or determining markers of prognosis
• To promote collaborative clinical, basic and translational research in NCFB between German (and European) centers
• To provide a registry of well phenotyped patients with NCFB in clinical centers potentially eligible for enrolment into clinical trials
• To track access to healthcare and cost of caring for patients with NCFB over time

Enrollment: 750 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A clinical history consistent with bronchiectasis
• (High resolution) computed tomography (CT) scan of the chest demonstrating bronchiectasis affecting 1 or more lobes

Exclusion criteria

• Bronchiectasis due to known cystic fibrosis (CF)
• Age <18 years
• Interstitial lung disease
• Prior lung or heart-lung transplantation