>The Purpose of This Study Was to Determine Whether Consuming a 100-mL Cup of Coffee is Effective in Preventing or Reducing Postoperative Ileus After Laparotomy of Benign Gynecological Patients

Rajavithi Hospital

Status: Completed

Conditions: Effects of Coffee Ingestion on Recovery of Bowel Function

Treatments: Other: caffeine coffee; Other: still water; Other: decaffiene coffee

Study type: Interventional

Funder types: Other

Identifiers

NCT03660267

coffeeaof

Details and patient eligibility

About

Comparison of the effectiveness coffee (with or without caffeine) ingestion and water for reducing the duration of Postoperative ileus after Laparotomy of Benign Gynecological Patients

Full description

laparotomy benign gynecological surgery is the most common gynecologic operation worldwide because is major operation for surgery and can affect to bowel movement after operation and turn to postoperative ileus , clinically severe postoperative ileus affects up to 14% of patients after laparotomy for gynecologic surgery that leaded to more complication, slowly recovery , prolong length of hospitalized stay and consequently increase unnecessary cost of treatment.

Preclinical studies has considered to use preventative therapeutic options for prevent ileus including coffee

The investigators used the coffee reduces postoperative ileus However, no good quality of evidence base supports the effectiveness coffee (with or without caffeine) ingestion and water for reducing the duration of Postoperative ileus after Laparotomy of Benign Gynecological Patients

Enrollment: 90 patients

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients were asked to participate if they were scheduled to undergo laparotomy for a benign gynecologic condition
• Ever drink coffee before
• can speak or communication Thai language

Exclusion criteria

1 hypersensitivity or allergy to caffeine/ coffee 2.ever intraabdominal sugery before 3. had an active intra-abdominal malignancy, bowel perforation, pre-existing bowel disease, or a history of abdominal or pelvic irradiation.

4.pregnancy woman 5.thyroid disease 6 Inflammatory bowel disease 7.liver disease 8.cardiac arrhythmia 9.history of difficult to defecation ( feces only 2 times per week) 10.after operation need to stay in ICU more than 24 hr 11.need to put Ng tube after operation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 3 patient groups

coffee group

Experimental group

Description:

caffeine coffee

Treatment:

Other: caffeine coffee

decaffeinete coffee group

Experimental group

Description:

decaffeinete coffee group

Treatment:

Other: decaffiene coffee

water group

Experimental group

Treatment:

Other: still water