The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy

Gia Dinh People Hospital

Status: Completed

Conditions: Anesthesia

Treatments: Other: Other

Study type: Interventional

Funder types: Other

Identifiers

NCT04712162

81/CN-HĐĐĐ

Details and patient eligibility

About

The good quality of recovery after general anesthesia is one of goals for short procedures and ambulatory surgeries. The study's objective was to compare the quality of recovery after general anesthesia with desflurane and sevoflurane with laryngeal mask airway for endoscopic ureteral lithotripsy.

Full description

This is a randomized controlled trial. There were 60 cases of endoscopic ureteral lithotripsy under general anesthesia with laryngeal mask airway were enrolled. All cases were randomly divided into two group (desflurane or sevoflurane). Each group had 30 cases. Primary outcome was time to awakening. Secondary outcomes were time to wash-out of volatile anesthetics, time to extubation, irritation after awakening, and modified Aldrete score.

Statistical analysis was performed by using Kaplan-Meieir curve and log-rank test for time to adequate depth of anesthesia and time to awakening; t-test for time to wash-out of volatile anesthetics; chi-square test for depth of anesthesia by PRST score, irritation after awakening and Aldrete score; Fisher test for adverse effects of volatile anesthetics.

The research was approved by Gia Dinh People Hospital ethics committee

Enrollment: 60 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All eligible subjects who underwent endoscopic ureteral lithotripsy under general anesthesia
• ASA I and II

Exclusion criteria

• Contraindication to laryngeal mask airway.
• Indication for conversion to tracheal intubation during surgery.
• History of malignant hyperthermia.
• Pregnancy.
• Obese (BMI >25 kg/m2).
• Substances abuse.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

D: maintain anesthesia with desflurane

Other group

Description:

D: maintain anesthesia with Suprane® (Desflurane) at 6%. Volatile concentration was titrated according to end-tidal MAC to maintain 0.7-1.3 MAC using end-tidal monitor of Dräger Primus anesthesia machine.

Treatment:

Other: Other

S: maintain anesthesia with sevoflurane.

Other group

Description:

S: maintain anesthesia with Sevorane® (Sevoflurane) at 2%. Volatile concentration was titrated according to end-tidal MAC to maintain 0.7-1.3 MAC using end-tidal monitor of Dräger Primus anesthesia machine.

Treatment:

Other: Other