The Rapid Shallow Breathing Index (RSBI) is a Widely Used Predictor for Weaning Patients From Mechanical Ventilation This Study Aims to Determine the Predictive Value of RSBI Measurements for Extubation Success in Mechanically Ventilated ICU Patients

Ain Shams University

Status: Enrolling

Conditions: Failure of Extubation; Ventilated Patient in Intensive Care

Study type: Observational

Funder types: Other

Identifiers

NCT07467265

FAMSU R39/2026

Details and patient eligibility

About

Early extubation in ICU patients is crucial for reducing complications of prolonged ventilation, including morbidity and mortality. The Rapid Shallow Breathing Index (RSBI) is a widely used predictor for weaning patients from mechanical ventilation. This study aims to determine the predictive value of RSBI measurements for extubation success in mechanically ventilated ICU patients

Full description

The extubation decision is a combined clinical judgment based on a passing Spontaneous Breathing Trial (SBT) and a Rapid Shallow Breathing Index (RSBI) value ≤ 105 breaths/min/L.combination of criteria (SBT + RSBI threshold) This approach is recommended to improve predictive accuracy, as neither SBT nor RSBI alone is perfectly reliable.

Enrollment: 70 estimated patients

Sex: All

Ages: 22+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Adults > 22 years.

  • Mechanically ventilated patients meeting extubation readiness:

    • FiO₂ ≤ 0.4, PEEP ≤ 8 cmH₂O, PaO₂/FiO₂ ≥ 200 mmHg.
    • Respiratory rate ≤ 35 breaths/min, pH > 7.30.
    • Hemodynamic stability (HR ≤ 120 bpm, SBP 90-160 mmHg).
    • Glasgow Coma Scale >10, adequate cough reflex.

  • Includes postoperative, elective/emergency reintubation, and tracheostomized patients.

Exclusion criteria

• Age <22 years.
• Refusal of informed consent.
• Altered mental status (e.g., traumatic brain injury).
• Hemodynamic instability or deep sedation (RASS ≤ -2).