The Relationship Between Blood Glucose and Satiety Ratings

Western University, Canada

Status: Unknown

Conditions: Satiety; Appetite

Treatments: Dietary Supplement: Mirexus PhytoSpherix supplementation; Behavioral: satiety ratings; Dietary Supplement: Generation UCAN supplementation

Study type: Interventional

Funder types: Other

Identifiers

NCT04183855

115099

Details and patient eligibility

About

Participants will be given a drink (and no drink for one of the treatments) prior to a pizza dinner. Ratings on satiety, appetite and desire to eat will be asked with the use of a questionnaire. Blood glucose will also be measured. One hour after the drink, participants will be given a pizza and can eat as much as they want. The pizza remaining will be weighed.

Full description

Each participant will receive all three treatments on separate occasions in random order (separated by a week). The three treatments include control (no supplement), carbohydrates - protein (Generation UCAN supplement, 250ml, 10% solution) and carbohydrates alone (Mirexus PhytoSpherix, 250ml, 10% solution). Participants will report to the lab between 4-5 pm and 4 hours after their last meal on day they have not exercised. Participants will record food intake the day of the first experiment and will be asked to replicate both type and quantity for subsequent visits. Upon arrival at the lab, baseline measures (blood glucose as well as rating of satiety ratings, appetite and desire to eat (10-point visual analogue scale). Then the treatment will be given and all the aforementioned variables will be remeasured at 15, 30, 45 and 60 minutes post drink. At 65 minutes, participants will be provided with an ad libitum pizza meal. Participants will be told to eat until they are "comfortably full" (Bellissimo et al., 2008). The pizza provided will be weighed initially and once the participant is done eating and has left the lab, the remaining pizza will be weighed and recorded. The pizza will be a cheese only pizza to minimize any difference in energy intake due to the location of additional items placed on the pizza.

Participants will not be told the true purpose of this experiment, instead they will be told that the pizza meal is a reward for participating in the study. Later, at the conclusion of the study all will be debriefed.

Enrollment: 24 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy males and females at the age of 18-40
• sedentary individuals

Exclusion criteria

• exercise more than twice per week
• does not like pizza
• do not eat three meals a day
• medications that affect eating patterns
• have metabolic and gastrointestinal diseases

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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24 participants in 3 patient groups

control

Experimental group

Description:

no supplement will be provided on the day of the experiment

Treatment:

Behavioral: satiety ratings

Generation UCAN

Experimental group

Description:

carbohydrates - protein (Generation UCAN supplement, 250ml, 10% solution)

Treatment:

Behavioral: satiety ratings

Dietary Supplement: Generation UCAN supplementation

Mirexus PhytoSpherix

Experimental group

Description:

carbohydrates alone (Mirexus PhytoSpherix, 250ml, 10% solution)

Treatment:

Behavioral: satiety ratings

Dietary Supplement: Mirexus PhytoSpherix supplementation