The Relationship Between Diaphragm Muscle Thickness and Fibromyalgia

Gaziosmanpasa Research and Education Hospital

Status: Completed

Conditions: Diaphragm Issues; Fibromyalgia; Depression; Anxiety

Treatments: Diagnostic Test: Fibromyalgia study form; Diagnostic Test: Pulmonary function test; Diagnostic Test: Ultrasonographic Diaphragm Thickness Measurement

Study type: Observational

Funder types: Other

Identifiers

NCT06396949

97

Details and patient eligibility

About

Fibromyalgia syndrome is characterized by chronic pain, fatigue, sleep problems and functional symptoms. Fatigue, anxiety and depression disorders, poor quality of life, sleep disorders, decreased concentration, and impaired cognitive functions are non-specific pain-related symptoms.

Various studies have reported decreased chest expansion, maximal ventilatory volume and maximal expiratory pressure in fibromyalgia patients with widespread body pain. Additionally, dyspnea is a symptom associated with respiratory muscle weakness and is associated with general fatigue. In these individuals, lower data are obtained in daily living activities and general health evaluation surveys. We did not find any study in the literature regarding the relationship between diaphragm thickness and fibromyalgia symptoms. In the light of these data, we aimed to evaluate the thickness of the diaphragm, one of the most important inspiratory muscles, in fibromyalgia patients.

Full description

Demographic information of all individuals included in the study will be collected. Daily living activity will be evaluated with Short Form-36 (SF-36), Fibromyalgia Impact Questionnaire (FIQ), Pittsburgh Sleep Quality Questionnaire (PSQI) and Beck Depression Inventory. In order to evaluate the respiratory function test in both the fibromyalgia and control groups, three consecutive measurements will be taken with a hand spirometer and the arithmetic average of these three measurements will be recorded. In fibromyalgia and control patients, diaphragm thickness was measured at 8-9 degrees on the right anterior axillary line with a 6-14 Mhz linear, conventional ultrasound probe (Mindray DC-8, Shenzen Mindray Bio-Medical Electronics CO. LTD., P.R. China) in the supine position. It will be measured at the end of inspiration and expiration from the intercostal space. Three measurements will be made and the arithmetic average will be evaluated.

Enrollment: 45 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients diagnosed with fibromyalgia according to the 2016 ACR (American College of Rheumatology) diagnostic criteria without any comorbidities (such as liver, kidney failure, DM, rheumatic disease)
• Patients who underwent Pulmonary Function Test (PFT)
• Patients without pulmonary disease
• 18 -50 years old women and men

Exclusion criteria

• Congenital spinal, costal and diaphragmatic anomalies neuromuscular disease
• Respiratory system diseases that affect lung functions
• Patients who cannot cooperate with spirometry.
• Having surgery to the chest wall or spine
• Those with BMI > 25
• Those with liver, kidney failure, DM, rheumatic disease, neurological disease
• Individuals < 18 years and > 50 years old

Trial design

45 participants in 2 patient groups

Patient group

Description:

Volunteer men and women diagnosed with fibromyalgia to ACR (American College of Rheumatology) 2016 criteria between the ages of 18 and 50 who applied to our clinic will be included in our study

Treatment:

Diagnostic Test: Ultrasonographic Diaphragm Thickness Measurement

Diagnostic Test: Pulmonary function test

Diagnostic Test: Fibromyalgia study form

Control group

Description:

Healthy,volunteer men and women between the ages of 18-50 who applied to our clinic will be included in our study

Treatment:

Diagnostic Test: Ultrasonographic Diaphragm Thickness Measurement

Diagnostic Test: Pulmonary function test

Diagnostic Test: Fibromyalgia study form