the Relationship Between Helicobacter Pylori Infection and Irritable Bowel Syndrome

Sohag University

Status: Unknown

Conditions: Irritable Bowel Syndrome

Treatments: Diagnostic Test: H. pylori stool antigen

Study type: Observational

Funder types: Other

Identifiers

NCT04847401

Soh-Med-21-04-03

Details and patient eligibility

About

Evaluating any possible relationship between irritable bowel syndrome occurrence and Helicobacter pylori infection

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All patients will be selected according to Rome IV criteria for the diagnosis of IBS, which include:

Recurrent abdominal pain at least 1 day/week in the last 3 months, with two or more of the following criteria:

• Related to defecation
• Associated with a change in frequency of stool
• Associated with a change in form of stool. Criteria achieved for the last 3 months with symptom onset at least 6 months before diagnosis

Exclusion criteria

• • Rectal bleeding

  • Anemia
  • Weight loss
  • Onset after 50 years of age
  • Recent antibiotic use
  • Abnormal abdominal examination (organomegaly, lump)
  • Family history of colorectal cancer.
  • Family history of inflammatory bowel disease, or celiac disease.

Trial design

80 participants in 2 patient groups

Group 1

Description:

patients with Irritable Bowel Syndrome

Treatment:

Diagnostic Test: H. pylori stool antigen

Group 2

Description:

normal

Treatment:

Diagnostic Test: H. pylori stool antigen