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The Relationship Between Hormone Sensitivity and Imaging of Idiopathic Interstitial Pneumonia by Artificial Intelligence (IIP)

P

Peking University

Status

Completed

Conditions

Idiopathic Interstitial Pneumonia

Treatments

Radiation: high resolution CT

Study type

Observational

Funder types

Other

Identifiers

NCT05146934
LM2019173

Details and patient eligibility

About

Application of artificial intelligence deep learning algorithm to analyze the relationship between hormone sensitivity of idiopathic interstitial pneumonia and imaging features of high resolution CT.

Full description

Methods: the medical records and chest high-resolution CT images of patients with idiopathic interstitial pneumonia admitted to the respiratory department of the Third Hospital of Peking University from June 1, 2012 to December 31, 2020 were retrospectively analyzed.Application of artificial intelligence deep learning neural convolution network method to create recognition technology of different imaging features.Including ground glass, mesh, honeycomb, nodule or consolidation, the model was established. IIP patients were divided into hormone sensitive group and hormone insensitive group according to whether the use of hormone was effective or not.Logistic regression analysis was used to analyze the correlation between statistically significant parameters and hormone sensitivity.Artificial intelligence was used to establish the correlation model between imaging features and clinical data and hormone sensitivity.

Enrollment

150 patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Clinical-pathological-radiology diagnosis of idiopathic interstitial pneumonia Hormone therapy was used; The follow-up data were complete, and the effect of hormone use could be judged.

Exclusion criteria

Lung infection disease; Heart failure; Connective tissue disease; IIP Without hormone therapy ; IIP but the follow-up data were incomplete, and the effect of hormone use could not be judged.

Trial design

150 participants in 2 patient groups

Hormone sensitive group
Description:
Prednisone, 0.5mg/kgqd, 3-6months
Treatment:
Radiation: high resolution CT
Hormone insensitivity group
Description:
Prednisone, 0.5mg/kgqd, 3-6months
Treatment:
Radiation: high resolution CT

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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