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The Relationship Between Hypoalbuminemia and Development of Acute Kidney Failure (AKI) According to KDIGO Criteria

E

Erzincan University

Status

Unknown

Conditions

Hypoalbuminemia
Acute Kidney Failure

Treatments

Other: hypoalbuminemia

Study type

Observational

Funder types

Other

Identifiers

NCT03675906
ERZINCAN BINALI YILDIRIM

Details and patient eligibility

About

This study was designed to determine the association between preoperative and postoperative hypoalbuminemia and AKI in older age hip fracture surgeons, to determine which period of hypoalbuminemia contributes more to AKI development, the incidence of AKI according to anesthesia type, the presence of other factors affecting AKI development, the duration of hospitalization and cost- to be investigated.

Enrollment

160 estimated patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients with femur fracture surgery
  • 65 years and over
  • Patients with ASA I - IV physical condition
  • patients with spinal anesthesia or peripheral nerve block

Exclusion criteria

  • Patients undergoing emergency surgery
  • patients with preoperative serum creatinine (sCr) level> 1.5 mg / dl
  • patients with low serum albumin levels in both preoperative and postoperative periods
  • patients receiving preoperative ventilator care
  • patients with spinal anesthesia or peripheral nerve block contraindications (coagulopathies, local infection at the puncture site, spot infection) or nonsteroidal antiinflammatory drug (NSAID)

Trial design

160 participants in 4 patient groups

preoperative albumin levels <3.8
Treatment:
Other: hypoalbuminemia
preoperative albumin level >3.8
Treatment:
Other: hypoalbuminemia
postoperative Day 2 albumin level <2.9
Treatment:
Other: hypoalbuminemia
postoperative Day 2 albumin level >2.9
Treatment:
Other: hypoalbuminemia

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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