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The Relationship Between Left Atrial Pressure and Cardiac Function After Atrioventricular Node Ablation (LAP-TOP)

T

Tongji University

Status

Completed

Conditions

Atrial Fibrillation

Treatments

Procedure: left atrial pressure regulation

Study type

Interventional

Funder types

Other

Identifiers

NCT05449158
LAP-TOP

Details and patient eligibility

About

Effects of left atrial pressure-guided ventricular rate changes on cardiac function after atrioventricular node ablation combined with left bundle branch pacing

Full description

Effects of left atrial pressure-guided ventricular rate changes on cardiac function after atrioventricular node ablation combined with left bundle branch pacing. For patients with non-valvular atrial fibrillation who received atrioventricular node ablation combined with left bundle branch pacing in our hospital, a left atrial pressure catheter was used to monitor atrial pressure during the operation, and a lower average atrial pressure was obtained by adjusting the pacing frequency of the pacemaker. In a randomized controlled manner, the postoperative echocardiography, cardiothoracic ratio, cardiac function, etc. were compared between patients without atrial pressure monitoring and those who received atrial pressure adjustment, in order to clarify the effect of left atrial pressure-guided ventricular rate adjustment on atrioventricular node ablation combined with left bundle Benefit of pacing patients.

Enrollment

140 patients

Sex

All

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

18-85 years old atrial fibrillation patients

Exclusion criteria

There is a history of pacemaker implantation; patients after coronary artery bypass grafting; severe coronary stenosis or occlusion cannot be treated with reperfusion;

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

140 participants in 2 patient groups

LAP Group
Experimental group
Description:
Control of left atrial pressure changes by adjusting pacemaker frequency
Treatment:
Procedure: left atrial pressure regulation
Control Group
No Intervention group
Description:
General pacemaker rate setting

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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