The Relationship Between Maximal Oxygen Consumption and Inspiratory Muscle Activation Pattern Under Loaded Inspiratory Muscle Tests in Healthy Adults

National Taiwan University

Status: Completed

Conditions: Healthy

Treatments: Other: Loaded inspiratory muscle test and cardiopulmonary exercise test

Study type: Observational

Funder types: Other

Identifiers

NCT04463732

202005050RINA

Details and patient eligibility

About

Maximal oxygen consumption, VO2max, is the gold standard to evaluate human aerobic fitness, which stands for the maximal capacity of cardiorespiratory system and musculoskeletal system to transport and utilize oxygen. Previous study showed that there is significant correlation between maximal oxygen consumption from cardiopulmonary exercise test and strength and endurance of lower extremities. In people with sedentary lifestyle, they often limited by the lower limb muscle performance during cardiopulmonary exercise test. Their breathing patterns are more irregular than athletes during cardiopulmonary exercise test. However, there is no study comparing the activation pattern of respiratory muscles between these two groups. Whether the breathing pattern in people with lower exercise capacity is less efficient under exertional activities still unknown. The purpose of this study is to investigate the relationship between maximal oxygen consumption and inspiratory muscle activation pattern in healthy adults.

Enrollment: 10 patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults (age > 20 years old)
• Be able to cooperate with the measurements of this study

Exclusion criteria

• any clinical diagnosis that will influence the measurement, including any history of neuromyopathy
• angina, acute myocardial infarction in the previous one month
• pregnancy
• history of syncope during exercise
• any musculoskeletal system disorder that unable to perform cardiopulmonary exercise test

Trial design

10 participants in 1 patient group

Healthy group

Description:

Subjects are above 20 years old. Their condition is healthy with no history of inspiratory disease. They can cooperate with the measurements of this study.

Treatment:

Other: Loaded inspiratory muscle test and cardiopulmonary exercise test