The Relationship Between Microbiota and Coronary Ectasia

Konya Beyhekim Training and Research Hospital

Status: Completed

Conditions: Coronary Ectasia; Microbial Disease

Treatments: Diagnostic Test: Taking blood for kit study

Study type: Observational

Funder types: Other

Identifiers

NCT06384703

201518015

Details and patient eligibility

About

Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ. In addition, the microbiota, through its metabolites, is involved in the pathophysiology or progression of a wide range of diseases, from atherosclerotic diseases to metabolic diseases and even neurological diseases. Among these metabolites, trimethylamine n-oxide metabolite has been shown to be particularly effective on atherosclerotic heart diseases.

Enrollment: 2 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• over 18 years old
• not having occlusive coronary artery disease
• having coronary ectasia

Exclusion criteria

• patients with chronic kidney disease,
• revascularized coronary artery disease,
• previously documented critical coronary stenosis,
• acute or chronic inflammatory disease,
• rheumatologic disease,
• known active malignant disease,
• heart failure,
• moderate-to-severe valvular pathology
• patients who were on any steroid or immunosuppressive therapy

Trial design

2 participants in 2 patient groups

coronary ectasia cohort

Description:

Patients with coronary ectasia detected on coronary angiography and without any exclusion criteria were included.

Treatment:

Diagnostic Test: Taking blood for kit study

normal coronary cohort

Description:

Patients who underwent coronary angiography and did not have any of the exclusion criteria

Treatment:

Diagnostic Test: Taking blood for kit study