The Relationship Between Post-ERCP-choledocholithiasis and Gallbladder Status

Hepatopancreatobiliary Surgery Institute of Gansu Province

Status: Completed

Conditions: Cholecystitis

Treatments: Procedure: ERCP

Study type: Observational

Funder types: Other

Identifiers

NCT04234126

Gallbladder status and PEC

Details and patient eligibility

About

In this retrospective study, the investigators evaluate the relationship of post-ERCP-choledocholithiasis(PEC ) and the gallbladder status as a risk factor.

Full description

When patients have common bile duct(CBD) stones, ERCP is widely used for stone extraction instead of clinical operation. ERCP has many advantages like less injury or faster recovery. However, according to literature, ERCP will has a mostly 10% possibility to get an acute purulent cholecystitis, which often requires emergency intervention, therefore, it is necessary to know if the gallbladder status(chronic disease) is one of the important risk factors of PEC like the gallbladder wall thickness, chronic cholecystitis, polyps,crudely or calculus.

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Enrollment: 1,117 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Routine ERCP for CBD stone patients with gallbladder in situ

Exclusion criteria

• Unwillingness or inability to consent for the study
• Unstable vital signs Coagulation dysfunction (INR>1.5) and low peripheral blood platelet count (<50×10 ^9 / L) or using anti-coagulation drugs
• Any Prior surgery for CBD including ERCP
• Preoperative coexistent diseases: acute pancreatitis, GI tract hemorrhage, severe liver disease (such as decompensated liver cirrhosis, liver failure and so on), septic shock
• Biliary- duodenal fistula confirmed during ERCP
• Pregnant women or breastfeeding