The Relationship Between Preoperative Anxiety and Postoperative Delirium in Elderly Chinese Patients

Chinese PLA General Hospital (301 Hospital)

Status: Completed

Conditions: Cohort Studies

Study type: Observational

Funder types: Other

Identifiers

NCT06861764

PLAGH-PA-PD

Details and patient eligibility

About

This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the the relationship between Preoperative Anxiety and Postoperative Delirium in Elderly Chinese Patients: a Multicenter Prospective Cohort

Full description

This is a retrospective cohort study using prospective data from a multicenter database. 8000 elderly patients undergoing elective non-cardiac or non-neurosurgical surgery were included in this study. The Generalized Anxiety Disorder Scale (GAD-7) was used to measure preoperative anxiety symptoms. The confusion assessment method (3D-CAM) was used to assess postoperative delirium in elderly patients undergoing non-cardiac surgery. If the patient is discharged, follow up by phone or email. Binary logistic regression analysis and propensity score matching (PSM) and subgroup analysis were used to analyze the data.

Enrollment: 8,000 patients

Sex: All

Ages: 65 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• elderly patients (age ≥ 65 years)
• non-cardiac surgery, non-neurosurgical surgery

Exclusion criteria

• History of neurological or psychiatric disorders or use of neuropsychiatric drugs;
• Impaired cognitive function or inability to cooperate with preoperative follow-up;
• Sent to ICU after surgery;
• Deletional delirium outcome;
• Baseline missing >5%

Trial design

8,000 participants in 2 patient groups

Preoperative anxiety

Description:

According to the GAD-7 scale, the population was defined as the Preoperative anxiety group

Non-preoperative anxiety

Description:

According to the GAD-7 scale, the population was defined as the Non-preoperative anxiety group