The Relationship Between Structure and Visual Function in Myopia Foveoschisis

Sun Yat-sen University

Status: Suspended

Conditions: High Myopia

Treatments: Procedure: macular buckling surgery

Study type: Observational

Funder types: Other

Identifiers

NCT02915133

2016HM-MF

Details and patient eligibility

About

Macular foveoschisis (MF) is a common complication of pathological myopia, which is characterized by choroid-retinal degeneration and vision impairment. Although pars plana vitrectomy (PPV) is the primary method for MF treatment, there is still a large proportion of recurrent MF due to the extremely long global axial length and posterior staphyloma. Macular buckling (MB) surgery aims at counteracting the traction exerted by the posterior staphyloma, and has been proven an effective method for treating MF. Optical Coherence Tomography (OCT) is widely used for the structural analysis of MF. Multifocol electroretinogram (mfERG) is an objective examination for visual evaluation. To our knowledge, there is a lack of data on the comprehensive visual function evaluations of MF patients associated with OCT findings. Our clinical trial aims to provide the structural and functional relationship in MF patients undergoing MB surgery, and find out potential factors to determine the visual prognosis.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. axial length ≥ 26.5 mm or refractive error (spherical equivalent) ≥ 8.0 diopter;
2. macular foveoschisis that requires surgical intervention.

Exclusion criteria

1. ocular trauma or surgery history;
2. glaucoma, diabetic retinopathy;
3. intraocular active hemorrhage or inflammation;
4. unable to coordinate the OCT, mfERG, or other ophthalmological examinations.

Trial design

20 participants in 1 patient group

MF-MB

Description:

Consecutive participants with high myopic foveoschisis are scheduled to macular buckling (MB) surgery.

Treatment:

Procedure: macular buckling surgery