The Relationship of PRL and Polycystic Ovary Syndrome (PCOS) in Taiwan's Women

Taipei Medical University

Status

Completed

Conditions

Polycystic Ovary Syndrome

Study type

Observational

Funder types

Other

Identifiers

NCT01117272

WFH-PCOS-98009

Details and patient eligibility

About

Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder of reproductive-age women. According to Rotterdam 2003 criteria: at least two of three criteria are met, hyperandrogenism, chronic anovulation, and polycystic ovary. PCOS will cause irregular menstrual cycle, infertility, acne, hirsutism, obesity, or/and metabolic syndrome, diabetes that may increase risk of cardiovascular disease.

Hyperprolactinaemia is also a common problem in reproductive aged women. Both hyperprolactinaemia and PCOS had endocrine disorder and irregular menstrual cycle. Investigators hope to collect clinical data from PCOS and prolactinemia patients followed in Wang Fang hospital for many years in endocrinological and metabolical aspects for comparison. Investigators at the same time would like to understand more about other similarities and differences between these two endocrinological dysfunction for future study.

Enrollment

474 patients

Sex

Female

Ages

15 to 45 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

PCOM by ultrasound Diagnosis
Anovulation, Oligo menses
Hyperandrogenism

Exclusion criteria

Women who had been diagnosed with other etiology that should be excluded in PCOS diagnosis, such as hyperprolactinemia, hypogonadotropic hypogonadism, premature ovarian failure, congenital adrenal hyperplastic, androgen-secreting tumor, Cushing's syndrome, disorders of uterus( such as Asherman's syndrome, Mullerian agenesis), chromosomal anomalies( such as Turner syndrome).
Women who did not have sufficient clinical or biochemical records.
Girls who had menarche at <3 years of age and women who were >40 years of age.